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The sedative xylazine is starting to permeate illegal opioids and cocaine. It does not respond to naloxone, an overdose reversal medication, and may be to blame for grisly injuries and infections.

For months, governors of Texas and Arizona have been sending charter buses full of migrants to Washington, D.C., and now New York City. Neither local nor federal officials greet them when they arrive.

Kari Lake, who has spent her campaign spreading election lies, was endorsed by Trump. Her rival, Karrin Taylor Robson, was backed by Arizona Gov. Doug Ducey and former Vice President Mike Pence.

Police investigating the killings of four people in a small northeast Nebraska city have arrested a neighbor of the victims, the Nebraska State Patrol said.

Children's book writer Matt de la Pena and poet and essayist Hanif Abdurraqib talk about how basketball feeds their writing.

One young man has struggled to get himself and his mom out of Russian-occupied territory in southern Ukraine as fighting there intensifies.

NPR's Ailsa Chang speaks with Amanda Morris about how sign language evolves over time, the subject of her recent piece in The New York Times.

The chair of Iowa City’s Truth and Reconciliation Commission is in hot water over disparaging comments she made in a now-deleted podcast. But for now, it appears she’ll keep her seat.

Drought conditions have expanded across the state at a critical time for corn and soybean crops.

Declaring a public health emergency can free up resources to help the administration respond to the monkeypox outbreak. So far more than 6,000 people in the U.S. have been infected.