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In the past week, the U.S. has blown past record levels of infection that were seen in the summer, when new cases topped 77,000 in July.

State Sen. Mariannette Miller-Meeks is making her fourth bid for Iowa's 2nd Congressional District. The southeast Iowa seat was long-held by a Democrat, but President Donald Trump carried it in 2016. Now that the seat is open, it's considered a toss-up.

In the Rockies, small hospitals have no place to send patients when city hospitals are filling up. They report having to hold critical patients longer or transfer them far away, often out of state.

You would rather be Democrat Joe Biden heading into Election Day than President Trump, but there's lots of uncertainty. It's possible to see Biden win a blowout or Trump again eke out a win.

The Harrison County Board of Supervisors approved requiring face masks in the county to help curb the spread of COVID-19, as the county has seen an increase in coronavirus cases in the last few weeks.

Iowa’s top election official says he is confident the state’s voting system is prepared to stand up to any potential cyberattacks aimed at disrupting the election.

NPR's Mary Louise Kelly talks with Ben Ginsberg, a top Republican election lawyer, about Supreme Court rulings that blocked an attempt to challenge ballot deadlines in two swing states.

President Trump promised to end America's opioid crisis. On his watch overdose deaths flattened in 2018 then surged again to record levels.

The city recorded zero new coronavirus cases on Monday, for the first time since June. "Now is the time to congratulate every single Victorian for staying the course," said the state's top official.

As Iowa continues to see new record highs for COVID-19 hospitalizations, public health experts are warning it could have catastrophic effects on the state’s hospitals with winter on the horizon.