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As the year comes to an end, many of the world's most urgent security threats promise to spill over into 2022.

From Dr. Anthony Fauci to Sacha Baron Cohen, the year's most popular Fresh Air web pages reflect the show's strength as a place where artists, authors and journalists speak to the moment.

New research released by the Centers for Disease Control and Prevention found roughly 932,000 fatal overdoses from 1999-2020. Preliminary data shows another 100,000 deaths this year.

Multi-level marketing distributors claim to sell life-changing products. They’re also selling something else -- misleading product claims and disinformation.

A father and son accused of taking part in the January 6th attack on the U.S. Capitol are expected to plead guilty to federal charges in a hearing next week. Iowa health officials are reporting COVID-19 hospitalizations have dropped for the second week in a row. Plus, trace amounts of the toxic compounds known as PFAS were detected in well water and drinking water in West Des Moines as part of statewide monitoring by the Iowa DNR.

Billboard reports that last week was the best week for vinyl record sales in three decades. Adele's 30 was the top-selling vinyl album of the year. Taylor Swift's Red also broke vinyl sale records.

NPR pop culture critic Linda Holmes lists highlights from the year, including Ted Lasso, a TikTok dog, a twisty mystery, some great performances, and a moment in a mall.

After a strong harvest and commodity price jumps, many farmers are buying equipment to lower their tax burdens. But increased demand and soaring prices make it harder for young farmers to thrive.

As part of a response to a tornado a decade ago that killed more than 160 people, the Missouri city of Joplin developed a peer-to-peer mental health program that's been widely replicated.

The supply chain backlog has ships backed up off the coast of Los Angeles. They're spewing exhaust that's affecting the air quality in Southern California and renewing environmental health concerns.